„The Laboratory of Biochemistry and Molecular Biology of Germ Cells“
deals with understanding the function of the oocyte (egg)
and its fertilisation as well as the subsequent development of a new offspring.
„We are interested in the molecular processes within the egg
that lead to the development of a new healthy individual.“
We focus primarily on the study of cell division – meiosis and translation regulation,
i.e. the transcription of DNA segments into proteins.
For even the slightest errors during these processes
lead to poor oocyte quality and impaired early embryonic development.
„We use a laboratory mouse as mammalian model.“
For example, we have now created a mouse line where the female is “infertile”,
which allows us to study the mechanisms that would cure this infertility.
„Why is our work important?
We are trying to understand the fundamental cellular processes of oocyte development.
We are trying to solve the mammalian infertility
as well as the abnormalities in oocyte and embryo development.